Series A
$12M
Double Point Ventures · Lead
Open roles0
Total raised$12M
Team size11-50
Founded · StageSeries A
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About the company
What they build and who they serve.
Lighthouse Pharmaceuticals is a Novato, California clinical-stage biopharmaceutical company developing small-molecule therapies for chronic neurodegenerative and inflammatory diseases. Its lead program, LHP588, is an oral, once-daily gingipain inhibitor in a Phase 2 trial (SPRING) targeting P. gingivalis-positive Alzheimer's disease, supported by a $49.2M NIA grant. The company recently relocated its headquarters to the Buck Institute for Research on Aging.
Why it matters
Signals from funding, traction, and product direction.
- Round led by Double Point Ventures with participation from new and existing (unnamed) investors; Campbell Murray, M.D., DPV partner, joins Lighthouse's Board of Directors.
- Financing complements a $49.2M NIH/NIA grant (Award R01AG088524) supporting the Phase 2 SPRING trial of LHP588 in P. gingivalis-positive Alzheimer's patients.
- Lead asset LHP588 is an oral, once-daily small-molecule gingipain inhibitor targeting P. gingivalis, a periodontal-disease bacterium implicated in Alzheimer's pathogenesis.
- Company recently relocated headquarters to the Buck Institute for Research on Aging in Novato, California; led by CEO Casey Lynch.
Funding history
Rounds and investors over time, newest first.
In the news
Press, announcements, and coverage about this company.
Investors
Double Point Ventures
Focus areas
Series ABiotechnologyClinical TrialsHealthtechPharmaceuticals
No open roles on the board yet
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