Jack Hu
Co-Founder
Open roles0
Total raised$20M
Team size11-50
Founded · Stage2021 · Series A
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About the company
What they build and who they serve.
Pumpkinseed is a Palo Alto-based protein sequencing company developing deSIPHR, a nanophotonic chip platform that reads proteins de novo from molecular vibrations using high-throughput Raman spectroscopy. With over 100 million sensors per square centimeter fabricated via standard semiconductor processes, the platform identifies known and unknown proteins at single-molecule resolution — including post-translational modifications and non-canonical residues that mass-spectrometry tools miss. The company sells proteomic data to biopharma and biosecurity partners and is generating the high-resolution datasets that virtual cell models and AI-driven drug discovery require.
Team & contacts
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Why it matters
Signals from funding, traction, and product direction.
- Co-led by NfX (Omri Amirav-Drory) and Future Ventures (Steve Jurvetson, Maryanna Saenko); participation from Base4 Capital, ADVentures (Analog Devices CVC), and Stanford.
- Pumpkinseed has secured over $12M in committed near-term revenue through active contracts with Genentech, DARPA, and BARDA across immunology, precision medicine, and biothreat detection.
- Proprietary deSIPHR (de novo Sequencing and Identification of Proteins with High-throughput Raman) nanophotonic chip carries 100M sensors per square centimeter and amplifies Raman scattering over 10 million-fold for single-molecule reads.
- The company plans a $30-40M Series B within the next year per executive chairwoman Jen Dionne (Axios Pro). Co-founders: Stanford professor Jennifer Dionne, Dr. Jack Hu, and Dr. Nhat Vu.
Funding history
Rounds and investors over time, newest first.
Series A
$20MNFX · LeadFuture Ventures · LeadADVentures (Analog Devices, Inc.)Stanford UniversityBase4 Capital
In the news
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Investors
NFXFuture VenturesADVentures (Analog Devices, Inc.)Stanford UniversityBase4 Capital
Focus areas
Series ADeep TechBiotechnologyHealthtech
No open roles on the board yet
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