Series B
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About the company
What they build and who they serve.
Ray Therapeutics is a Berkeley, California clinical-stage biopharmaceutical company developing optogenetic gene therapies to restore vision in patients with retinal degenerative diseases. Its approach delivers a bioengineered, highly light-sensitive protein to surviving retinal cells via a single intravitreal injection, aiming to restore functional sight regardless of the underlying genetic mutation. Lead candidate RTx-015 is in clinical development for retinitis pigmentosa and holds FDA Regenerative Medicine Advanced Therapy (RMAT) designation, while second program RTx-021 targets macular conditions such as Stargardt disease and geographic atrophy.
Why it matters
Signals from funding, traction, and product direction.
- The Series B was upsized and oversubscribed, signaling strong investor demand ahead of late-stage clinical readouts.
- The round closed weeks after the FDA granted Regenerative Medicine Advanced Therapy (RMAT) designation to lead candidate RTx-015 for retinitis pigmentosa, unlocking rolling review and potential priority review benefits.
- Lead investor Janus Henderson Investors called RayTx's optogenetic platform a first- and best-in-class technology, joined by new backers Adage Capital, Franklin Templeton, Invus, and Marshall Wace, with follow-on from 4BIO Capital, Deerfield, Merck's MRL Ventures, Norwest, Novo Holdings, and Platanus.
- RayTx's lead program RTx-015 is being evaluated in the Phase I ENVISION study (NCT06460844) in retinitis pigmentosa; second program RTx-021 is in a Phase I/II study (NCT07439887) for Stargardt disease and IND-enabling work for geographic atrophy.
Funding history
Rounds and investors over time, newest first.
- $125MNovo HoldingsJanus Henderson Investors · LeadInvusFranklin TempletonMarshall WaceDeerfield Management4BIO CapitalNorwest Venture PartnersPlatanusMRL Ventures FundAdage Capital Management
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