Startup profile

Ray Therapeutics

Series BBerkeley, California, United States$125M raised

Open roles0
Total raised$125M
Team size11-50
Founded · Stage2021 · Series B

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About the company

What they build and who they serve.

Ray Therapeutics is a Berkeley, California clinical-stage biopharmaceutical company developing optogenetic gene therapies to restore vision in patients with retinal degenerative diseases. Its approach delivers a bioengineered, highly light-sensitive protein to surviving retinal cells via a single intravitreal injection, aiming to restore functional sight regardless of the underlying genetic mutation. Lead candidate RTx-015 is in clinical development for retinitis pigmentosa and holds FDA Regenerative Medicine Advanced Therapy (RMAT) designation, while second program RTx-021 targets macular conditions such as Stargardt disease and geographic atrophy.

Why it matters

Signals from funding, traction, and product direction.

  • The Series B was upsized and oversubscribed, signaling strong investor demand ahead of late-stage clinical readouts.
  • The round closed weeks after the FDA granted Regenerative Medicine Advanced Therapy (RMAT) designation to lead candidate RTx-015 for retinitis pigmentosa, unlocking rolling review and potential priority review benefits.
  • Lead investor Janus Henderson Investors called RayTx's optogenetic platform a first- and best-in-class technology, joined by new backers Adage Capital, Franklin Templeton, Invus, and Marshall Wace, with follow-on from 4BIO Capital, Deerfield, Merck's MRL Ventures, Norwest, Novo Holdings, and Platanus.
  • RayTx's lead program RTx-015 is being evaluated in the Phase I ENVISION study (NCT06460844) in retinitis pigmentosa; second program RTx-021 is in a Phase I/II study (NCT07439887) for Stargardt disease and IND-enabling work for geographic atrophy.

Funding history

Rounds and investors over time, newest first.

  1. Series B

    $125M
    Novo HoldingsJanus Henderson Investors · LeadInvusFranklin TempletonMarshall WaceDeerfield Management4BIO CapitalNorwest Venture PartnersPlatanusMRL Ventures FundAdage Capital Management

In the news

Press, announcements, and coverage about this company.

Investors

Novo HoldingsJanus Henderson InvestorsInvusFranklin TempletonMarshall WaceDeerfield Management4BIO CapitalNorwest Venture PartnersPlatanusMRL Ventures FundAdage Capital Management

Focus areas

Series BBiotechnologyClinical TrialsHealthtechPharmaceuticals
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