JOB DETAILS

Chief Business Officer

CompanyGrafton Sciences
LocationSan Francisco
Work ModeOn Site
PostedDecember 6, 2025
About The Company
Grafton Sciences is pioneering AI systems with general physical ability, the capacity to experiment, engineer, or manufacture anything. By pairing this physical substrate with advanced learning architectures, our goal is to build superintelligence. Backed by leading partners, including ARPA-H, we are redefining how the physical world is queried at scale.
About the Role

About Grafton Sciences

We’re building AI systems with general physical ability, the capacity to experiment, engineer, or manufacture anything. We believe achieving this is a key step toward building superintelligence. With deep technical roots and real-world progress at scale (for example, a $42 million NIH program), we’re pushing the frontier of physical AI. Joining us means inventing from first principles, owning real systems end to end, and helping build a capability the world has never had before.

About the Role

We’re seeking a Chief Business Officer to lead the company’s commercial, partnership, and capital efforts. You will develop high-value relationships across industry and finance, shape the company’s external strategy, and build the business infrastructure required for rapid growth. This is a founder-level role for someone who can operate across partnerships, capital formation, finance, legal, and business operations, while collaborating closely with technical leadership.

Responsibilities

• Build and expand strategic partnerships with large companies across manufacturing, mobility, logistics, and advanced technology.
• Lead external engagement with investors, advising on capital strategy and preparation.
• Own commercial development, including early customer programs and business growth.
• Oversee business operations, finance, legal, and contracting processes as the company scales.
• Operate as a generalist and support any mission-critical business needs in a fast-moving environment.

Qualifications

• Strong network across industry and investment communities.
• Proven ability to lead commercial or strategic functions at high-growth or frontier-tech companies.
• Experience managing partnerships, customer programs, or strategic initiatives with senior stakeholders.
• Strong instincts across finance, operations, and organizational leadership.
• High-agency operator comfortable owning broad responsibilities end to end.

Above all, we look for candidates who can demonstrate world-class excellence.

Compensation

We offer competitive salary, meaningful equity, and benefits.

Key Skills
Strategic PartnershipsCapital StrategyCommercial DevelopmentBusiness OperationsFinanceLegalContractingOrganizational LeadershipPartnership ManagementCustomer ProgramsStakeholder EngagementHigh-Growth CompaniesFrontier-Tech CompaniesGeneralist SkillsFast-Moving EnvironmentWorld-Class Excellence
Categories
Management & LeadershipTechnologyFinance & Accounting
Benefits
Competitive SalaryMeaningful EquityBenefits
Job Information
📋Core Responsibilities
The Chief Business Officer will build and expand strategic partnerships, lead external engagement with investors, and oversee business operations as the company scales. This role requires collaboration with technical leadership and support for mission-critical business needs.
📋Job Type
full time
📊Experience Level
10+
💼Company Size
5
📊Visa Sponsorship
No
💼Language
English
🏢Working Hours
40 hours
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