JOB DETAILS

Founding Commercial Lead

CompanyGrafton Sciences
LocationSan Francisco
Work ModeOn Site
PostedDecember 6, 2025
About The Company
Grafton Sciences is pioneering AI systems with general physical ability, the capacity to experiment, engineer, or manufacture anything. By pairing this physical substrate with advanced learning architectures, our goal is to build superintelligence. Backed by leading partners, including ARPA-H, we are redefining how the physical world is queried at scale.
About the Role

About Grafton Sciences

We’re building AI systems with general physical ability, the capacity to experiment, engineer, or manufacture anything. We believe achieving this is a key step toward building superintelligence. With deep technical roots and real-world progress at scale (for example, a $42 million NIH program), we’re pushing the frontier of physical AI. Joining us means inventing from first principles, owning real systems end to end, and helping build a capability the world has never had before.

About the Role

We’re seeking a Founding Commercial Lead to build the company’s early partnerships, customer relationships, and business infrastructure. You will establish and grow external engagements, support investor interactions, and build the core business processes needed for scale. This role is ideal for a high-agency generalist who is energized by operating across multiple domains and owning outcomes end to end.

Responsibilities

• Establish and grow relationships with partners, customers, and external stakeholders.
• Support investor engagement and contribute to capital strategy and preparation.
• Develop commercial programs, including contracting, customer workflows, and early revenue processes.
• Handle finance, legal, and business operations activities as the organization evolves.
• Step into any high-priority business area to create clarity and momentum.

Qualifications

• Network across industry and investment communities, with experience driving external initiatives.
• Background in partnerships, commercial strategy, operations, or similar functions in high-growth environments.
• Strong cross-functional instincts and ability to collaborate closely with technical teams.
• Founder-like mindset with comfort switching between strategic and hands-on work.
• Adaptable, fast learner able to navigate ambiguity and shifting priorities.

Above all, we look for candidates who can demonstrate world-class excellence.

Compensation

We offer competitive salary, meaningful equity, and benefits.

Key Skills
PartnershipsCommercial StrategyOperationsCross-Functional CollaborationAdaptabilityFast LearningInvestor EngagementBusiness InfrastructureCustomer RelationshipsHigh-Growth EnvironmentsLegal ActivitiesFinance ActivitiesBusiness OperationsStrategic ThinkingHands-On WorkGeneralist
Categories
TechnologyManagement & LeadershipSalesConsultingEngineering
Benefits
Equity
Job Information
📋Core Responsibilities
The Founding Commercial Lead will establish and grow relationships with partners, customers, and external stakeholders while supporting investor engagement. Additionally, they will develop commercial programs and handle finance, legal, and business operations activities as the organization evolves.
📋Job Type
full time
📊Experience Level
5-10
💼Company Size
5
📊Visa Sponsorship
No
💼Language
English
🏢Working Hours
40 hours
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